Unable to install on IIS/SSMS; 'No connection could be made because the target machine actively refused it'

I’m trying to set up a local site using IIS/SQL Server/SSMS

The database engine is running, the db exists, db user has been added with db_owner membership, but when I hit install I get the following message;

SQLSTATE[HY000] [2002] No connection could be made because the target machine actively refused it

Can anyone suggest a step I may have missed, or any probably cause/fix for this?

Cheers in advance.